GENERAL CATALOGUE
DOTAGA-FAP-2286-ALB
HY-173374 · 1 mg
MedChemExpress · Cat: HY-173374
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Catalog No: HY-173374
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
DOTAGA-FAP-2286-ALB is a derivative of Rofapitide tetraxetan HY-147057 . DOTAGA-FAP-2286-ALB is a selective fibroblast activation protein FAP inhibitor with an IC50 value of 67.5 nM. DOTAGA-FAP-2286-ALB enhances tumor retention via albumin interaction, prolonging blood circulation and improving radiometal complex stability e.g., with 111In and 225Ac . DOTAGA-FAP-2286-ALB is promising for research of radionuclide therapy TRT of FAP-positive solid tumors.
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