GENERAL CATALOGUE
DPP-21
HY-169096 · 50 mg
MedChemExpress · Cat: HY-169096
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medchemexpress.com/dpp-21.html
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Catalog No: HY-169096
CAS No: 2924883-83-8
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
DPP-21 is an inhibitor of tubulin polymerization IC50: 2.4 ?M . DPP-21 shows anti-proliferative activity against cancer cell lines, with IC50s of 0.38 nM HCT116 , 11.69 nM B16 , 5.37 nM HeLa , 9.53 nM MCF7 , 8.94 nM H23 and 9.37 nM HepG2 respectively. DPP-21 arrests the cell cycle in the G2/M phase of mitosis, subsequently inducing tumor cell apoptosis decreases Bcl-2 but upregulates the pro-apoptotic protein Bax .
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