GENERAL CATALOGUE
DPQ
HY-114869 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-114869
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Catalog No: HY-114869
CAS No: 129075-73-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DPQ is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ inhibits NF-?B pathway activation, reduces the expression of pro-inflammatory factors such as TNF-?, IL-6 and oxidative stress. DPQ can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases.
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