GENERAL CATALOGUE
DPQ hydrochloride
HY-W424851 · 50 mg
MedChemExpress · Cat: HY-W424851
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medchemexpress.com/dpq-hydrochloride.htmlCatalog No: HY-W424851
CAS No: 84050-22-6
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-?B pathway activation, reduces the expression of pro-inflammatory factors such as TNF-?, IL-6 and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases.
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