GENERAL CATALOGUE
DS-103
HY-173064 · 50 mg
MedChemExpress · Cat: HY-173064
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medchemexpress.com/ds-103.html
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Catalog No: HY-173064
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
DS-103 is an inhibitor for HDAC that inhibits HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8 with IC50s of 0.029, 0.123, 0.022, 0.367 and 9.26 ?M, respectively. DS-103 inhibits Plasmodium falciparum 3D7 with IC50 of 5.08 ?M. DS-103 exhibits cytotoxicity in cells A2780 and Cal27 with IC50 of 1.48 ?M and 1.47 ?M, reverses Cisplatin HY-17394 resistance in A2780 and Cal27 with IC50 of 4.62 ?M and 2.23 ?M. DS-103 exhibits synergistic effect with Cisplatin HY-17394 , enhances Cisplatin-induced apoptosis.
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