GENERAL CATALOGUE
DS-5272
HY-120667 · 1 mg
MedChemExpress · Cat: HY-120667
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Catalog No: HY-120667
CAS No: 1235575-97-9
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
DS-5272 is an orally acitve inhibitor for p53-MDM2 with an IC50 of 20 nM. DS-5272 inhibits the proliferation of SJSA-1 wildtype p53, IC50=0.17 ?M and DLD-1 mutant p53 . DS-5272 arrest the cell cycle, and induces apoptosis in SJSA-1. DS-5272 exhibits antitumor efficacy in mice.
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