GENERAL CATALOGUE
DSG-2/Desmoglein-2, His, Mouse
Z06090 · 100 ug
GenScript · Cat: Z06090
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Catalog No: Z06090
Category: protein
Pack Size: 100 ug
Brand: GenScript
Description
Desmoglein-2 DSG-2 as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.
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