GENERAL CATALOGUE
DSM705 hydrochloride
HY-132171A · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-132171A
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Catalog No: HY-132171A
CAS No: 2989908-08-7
Category: Anti-infection
Pack Size: Free Sample (0.1 - 0.2 mg)
Brand: MedChemExpress
Description
DSM705 hydrochloride, an orally active antimalarial compound, is a pyrrole-based Dihydroorotate Dehydrogenase DHODH inhibitor. DSM705 hydrochloride exhibits nanomolar potency against Plasmodium DHODH and Plasmodium parasites IC50=95, 52 nM for P. falciparum and P. vivax DHODH, respectively , with no inhibition of mammalian DHODHs.
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