GENERAL CATALOGUE
DSR-141562
HY-136569 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-136569
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Catalog No: HY-136569
CAS No: 2007975-22-4
Category: Metabolic Enzyme Protease
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 PDE1 inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.
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