GENERAL CATALOGUE
DTHIB
HY-138280 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-138280
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Catalog No: HY-138280
CAS No: 897326-30-6
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
DTHIB is a direct and selective heat shock factor 1 HSF1 inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain DBD . DTHIB inhibits HSF1 cancer gene signature HSF1 CaSig and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research.
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