GENERAL CATALOGUE
Duocarmycin SA
HY-12456 · 1 mg
MedChemExpress · Cat: HY-12456
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Catalog No: HY-12456
CAS No: 130288-24-3
Category: Anti-infection
Pack Size: 1 mg
Brand: MedChemExpress
Description
Duocarmycin SA is an orally active antitumor antibiotic with an IC50 of 10 pM. Duocarmycin SA is an extremely potent cytotoxic agent capable of inducing a sequence-selective alkylation of duplex DNA. Duocarmycin SA demonstrates synergistic cytotoxicity against glioblastoma multiforme GBM cells treated with proton radiation in vitro.
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