GENERAL CATALOGUE
DuP-697
HY-103387 · 5 mg
MedChemExpress · Cat: HY-103387
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medchemexpress.com/dup-697.htmlCatalog No: HY-103387
CAS No: 88149-94-4
Category: Apoptosis
Pack Size: 5 mg
Brand: MedChemExpress
Description
DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively . DuP-697 exerts antiproliferative IC50 of 42.8 nM , antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects.
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