

HY-170783 · 50 mg
MedChemExpress · Cat: HY-170783
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medchemexpress.com/dxr-in-4.htmlDescription
DXR-IN-4 Compound 12a is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXR . DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC50s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC50 of 11 ?M and 12 ?M.







