GENERAL CATALOGUE
DZ-837
HY-161989 · 1 mg
MedChemExpress · Cat: HY-161989
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Manufacturer product page
medchemexpress.com/dz-837.htmlCatalog No: HY-161989
Category: Immunology Inflammation
Pack Size: 1 mg
Brand: MedChemExpress
Description
DZ-837 compound 3d is a PROTAC targeting BCL6 with a DC50 of approximately 600 nM. DZ-837 can induce cell cycle arrest and exert synergistic anticancer effects with Ibrutinib HY-10997 . DZ-837 is composed of PROTAC target protein ligand BCL6 ligand-2 HY-161990 red part , E3 ubiquitin ligase ligand Thalidomide-4-OH HY-103596 blue part , and PROTAC Linker HY-W245803 black part , among which the conjugate of E3 ubiquitin ligase ligand + Linker is 2- 2,6-Dioxopiperidin-3-yl -4- 2-2-hydroxyethoxy ethyl aminoisoindoline-1,3-dione HY-W924949 1 .
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