GENERAL CATALOGUE
(E)-2-Hexadecenal
HY-121683 · 1 mg
MedChemExpress · Cat: HY-121683
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medchemexpress.com/e-2-hexadecenal.htmlCatalog No: HY-121683
CAS No: 22644-96-8
Category: Apoptosis
Pack Size: 1 mg
Brand: MedChemExpress
Description
E -2-Hexadecenal trans-2-Hexadecenal is an MLK3 activator that induces cytoskeletal remodeling, leading to cell rounding, detachment, and ultimately apoptosis in human and mouse cells. E -2-Hexadecenal activates the MLK3 signaling pathway, phosphorylating MKK4/7 and JNK, subsequently activating downstream targets of JNK, such as c-Jun phosphorylation, cytochrome c release, Bax activation, Bid cleavage, and Bim translocation to mitochondria. E -2-Hexadecenal has potential applications in research related to sphingolipid signaling pathways.
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