Cadherin 5 Rabbit Monoclonal Antibody

Description

EnkiLife offers the Cadherin 5 Rabbit Monoclonal Antibody. This antibody reacts with Mouse species and is suitable for WB,ICC/IF,IP application. Alternative Names of Immunogen: 7B4; Vec; VECD; Cd144; VEcad; VE-Cad; AA408225. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:1000,ICC/IF 1:50-1:200,IP 1:20-1:50 Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction. Research Area: Signal Transduction