GENERAL CATALOGUE
(E/Z)-Afatinib
HY-10261B · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-10261B
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Manufacturer product page
medchemexpress.com/e-z-afatinib.htmlCatalog No: HY-10261B
CAS No: 439081-18-2
Category: Apoptosis
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
E/Z -Afatinib E/Z -BIBW 2992 is the mixture of E -Afatinib and Z -Afatinib. Afatinib HY-10261 is an irreversible inhibitor of EGFR, by irreversibly binding to their ATP binding site to block activation of EGFR, HER2, HER4, and EGFRvIII. Afatinib used in co-administration with Temozolomide HY-17364 , potently targeting to EGFRvIII-cMet signaling in glioblastoma cells.
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