GENERAL CATALOGUE
E0924G
HY-168336 · 10 mM * 1 mL in DMSO
MedChemExpress · Cat: HY-168336
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Catalog No: HY-168336
CAS No: 2909474-29-7
Category: Cell Cycle DNA Damage
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress
Description
E0924G is an orally active activator for PPAR? with EC50 of 2.82 ?M. E0924G promotes the upregulation of osteoprotegerin OPG with an EC50 of 0.29 ?M. E0924G reduces RANKL-induced osteoclast differentiation and inhibites F-actin ring formation in RAW264.7 macrophages. E0924G regulates the bone density and bone loss in ovariectomized OVX and age-related osteoporosis models.
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