GENERAL CATALOGUE
E197
HY-164587 · 5 mg
MedChemExpress · Cat: HY-164587
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Catalog No: HY-164587
CAS No: 2378515-04-7
Category: Immunology Inflammation
Pack Size: 5 mg
Brand: MedChemExpress
Description
E197 is the inhibitor for DOCK5 that destroys the podosome belt structure of osteoclasts, thereby inhibiting the bone resorption IC50=3.44 ?M in human osteoclast . E197 inhibits the Rac in DOCK5 expressing HEK293 cell with an IC50 of 36 ?M. E197 prevents the bone loss in mouse ovariectomized models.
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