

HY-P10428 · 50 mg
MedChemExpress · Cat: HY-P10428
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Manufacturer product page
medchemexpress.com/e6ap-mimicking-peptide.html
Description
E6AP-mimicking peptide compound 13 is a high-affinity, selective, irreversible and potent peptide-based covalent HPV16 E6 inhibitor targeting the 16E6 oncoprotein using a cysteine-reactive acrylamide warhead. E6AP-mimicking peptide has a Ki of 17 nM. E6AP-mimicking peptide targets all residues appearing in the binding pocket of E6 to disrupt the binding interface of 16E6 and E6AP. E6AP-mimicking peptide selectively binds and crosslinks to MBP-16E6 in PBS or a protein mixture.







