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E7820
GENERAL CATALOGUE

E7820

HY-14571 · 10 mM * 1 mL in DMSO

MedChemExpress · Cat: HY-14571

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medchemexpress.com/E7820.html
Catalog No: HY-14571
CAS No: 289483-69-8
Category: Cytoskeleton
Pack Size: 10 mM * 1 mL in DMSO
Brand: MedChemExpress

Description

E7820 ER68203-00 , an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 ?g/ml. E7820 modulates ?-1, ?-2, ?-3, and ?-5 integrin mRNA expression. Antiangiogenic and antitumor activity.

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