

HY-173364 · 1 mg
MedChemExpress · Cat: HY-173364
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medchemexpress.com/eb-tcip.htmlDescription
EB-TCIP BAK-04-212 is a bivalent molecule comprised of AP1867 HY-114434 and BI-3812 HY-111381 . EB-TCIP can form a reversible ternary complex between FKBPF36V and BCL6BTB. EB-TCIP recruits FKBP12F36V-tagged EWS/FLI1 to DNA sites bound by the transcriptional regulator BCL6, leading to rapid expression of BCL6 target genes eg: SOCS2 and CXCL11 . EWS/FLI1 is a fusion transcription factors in Ewing sarcoma. EB-TCIP can be used for research of deregulated transcription in cancer.







