

HY-161346 · 1 mg
MedChemExpress · Cat: HY-161346
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medchemexpress.com/ebet-1055.htmlDescription
EBET-1055 is a bromodomain and extra-terminal BET PROTAC degrader. EBET-1055 effectively inhibits the growth of pancreatic ductal adenocarcinoma PDAC . EBET-1055 also simultaneously modulates cancer-associated fibroblast CAF activity, upregulating all reporter gene activities in organoid co-cultures. Pink: BET ligand HY-161387 ; Blue: CRBN ligase ligand HY-14658 ; Black: linker

