Ebselen derivative 1

Description

Ebselen derivative 1 Compound 19 is a glutathione peroxidase GPx mimic with oral activity. Ebselen derivative 1 demonstrates significant protective effects against cisplatin HY-17394 -induced hair cell HC damage both in vitro and in vivo, effectively reducing oxidative stress, apoptosis, and ferroptosis in hair cells. Ebselen derivative 1 can be utilized in the research of cisplatin HY-17394 -induced hearing loss .