EEA1 Rabbit Polyclonal Antibody

Description

EnkiLife offers the EEA1 Rabbit Polyclonal Antibody. This antibody reacts with Human,Mouse species and is suitable for WB,ELISA application. Alternative Names of Immunogen: EEA1; ZFYVE2; Early endosome antigen 1; Endosome-associated protein p162; Zinc finger FYVE domain-containing protein 2. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,ELISA 1:10000-1:20000 Background: disease:Antibodies against EEA1 are found in sera from patients with subacute cutaneous lupus erythematosus and other autoimmune diseases. domain:The FYVE-type zinc finger domain mediates interactions with phosphatidylinositol 3-phosphate. function:Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. similarity:Contains 1 C2H2-type zinc finger. similarity:Contains 1 FYVE-type zinc finger. subunit:Homodimer. Binds STX6. Binds RAB5A, RAB5B, RAB5C and RAB22A that have been activated by GTP-binding. Research Area:Endocytosis;