GENERAL CATALOGUE
EGFR/BRAFV600E-IN-1
HY-147825 · 50 mg
MedChemExpress · Cat: HY-147825
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Manufacturer product page
medchemexpress.com/egfr-brafv600e-in-1.htmlCatalog No: HY-147825
CAS No: 2492429-45-3
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR/BRAFV600E-IN-1 Compound 23 is a potent EGFR and BRAFV600E dual inhibitor with IC50s of 0.08 and 0.15 AAasAasAAmuM, respectively. EGFR/BRAFV600E-IN-1 induces apoptosis and cell cycle arrest in both pre-G1 and G2/M phases. EGFR/BRAFV600E-IN-1 exhibits antiproliferative activity againist A-549, MCF-7, Panc-1, HT-29 with IC50s of 1.2, 0.79, 1.3, and 1.23 AAasAasAAmuM, respectively.
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