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EGFR/CDK2-IN-3
GENERAL CATALOGUE

EGFR/CDK2-IN-3

HY-156115 · 50 mg

MedChemExpress · Cat: HY-156115

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Catalog No: HY-156115
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress

Description

EGFR/CDK2-IN-3 compound 4b is a dual inhibitor of EGFR and CDK-2 with IC50s of 71.7 and 113.7 nM, respectively. EGFR/CDK2-IN-3 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-3 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC50 of 3.16 ?M.

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