

HY-156115 · 50 mg
MedChemExpress · Cat: HY-156115
Reach 3+ verified distributors
Manufacturer product page
medchemexpress.com/egfr-cdk2-in-3.htmlDescription
EGFR/CDK2-IN-3 compound 4b is a dual inhibitor of EGFR and CDK-2 with IC50s of 71.7 and 113.7 nM, respectively. EGFR/CDK2-IN-3 induces apoptosis in MCF-7 cells and arrests the cell cycle in the S phase. EGFR/CDK2-IN-3 has significant anti-cancer cell toxicity and inhibits MCF-7 with an IC50 of 3.16 ?M.