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EGFR/DHFR-IN-2
GENERAL CATALOGUE

EGFR/DHFR-IN-2

HY-172897 · 50 mg

MedChemExpress · Cat: HY-172897

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Catalog No: HY-172897
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress

Description

EGFR/DHFR-IN-2 9b is a dual h-DHFR/EGFRTK inhibitor, with IC50 values of 0.192 ?M and 0.109 ?M for h-DHFR and EGFR, respectively. EGFR/DHFR-IN-2 9b halts the cell cycle at the G1/S phase and induces apoptosis. EGFR/DHFR-IN-2 9b is a potential inhibitor of CYP2C9 and CYP3A4. EGFR/DHFR-IN-2 9b can be used in the cancer research.

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