GENERAL CATALOGUE
EGFR/HDAC-IN-1
HY-173520 · 50 mg
MedChemExpress · Cat: HY-173520
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Manufacturer product page
medchemexpress.com/egfr-hdac-in-1.htmlCatalog No: HY-173520
Category: Cell Cycle DNA Damage
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR/HDAC-IN-1 Compound 22c2 is a potent dual inhibitor of epidermal growth factor receptor EGFR and histone deacetylase HDAC with IC50 values of 4.81 nM, 119.4 nM and 354.8 nM for EGFR, HDAC1 and HDAC3, respectively. EGFR/HDAC-IN-1 blocks the EGFR signaling pathway and affects the histone acetylation status, thereby inhibiting tumor cell proliferation. EGFR/HDAC-IN-1 is promising for research of non-small cell lung cancer NSCLC .
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