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EGFR/HER2/DHFR-IN-2
GENERAL CATALOGUE

EGFR/HER2/DHFR-IN-2

HY-149632 · 50 mg

MedChemExpress · Cat: HY-149632

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Catalog No: HY-149632
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress

Description

EGFR/HER2/DHFR-IN-2 Compound 4b is an inhibitor of EGFR, HER2, and DHFR IC50: 0.248, 0.156, 0.138 ?M respectively . EGFR/HER2/DHFR-IN-2 has anticancer activities against a panel of cancer cells IC50: 9.14, 7.33, 14.18, 24.87, 20.07, 6.16 ?M for Hep G2, HeLa, HEp-2, HCT 116, PC-3, MCF7 cells . EGFR/HER2/DHFR-IN-2 reduce breast cancer tumor growth.

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