GENERAL CATALOGUE
EGFR/HER2/DHFR-IN-3
HY-149633 · 50 mg
MedChemExpress · Cat: HY-149633
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Manufacturer product page
medchemexpress.com/egfr-her2-dhfr-in-3.htmlCatalog No: HY-149633
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR/HER2/DHFR-IN-3 compound 4c is a potent dual inhibitor of EGFR/HER2, with IC50s of 0.138 and 0.092 ?M, respectively. EGFR/HER2/DHFR-IN-3 also inhibits DHFR, with an IC50 of 0.193 M. EGFR/HER2/DHFR-IN-3 causes arrest at the S phase of the cell cycle and induces apoptosis in MCF7 breast cancer cells.
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