EGFR/HER2-IN-17

Description

EGFR/HER2-IN-17 Compound 7h is a dual inhibitor of epidermal growth factor receptor EGFR and human epidermal growth factor receptor 2 HER2 . EGFR/HER2-IN-17 inhibits cancer cell proliferation. EGFR/HER2-IN-17 interacts with the binding pockets of EGFR and HER2, activating caspase-3 and caspase-8, and decreases the expression of Bcl-2, thereby inducing apoptosis. EGFR/HER2-IN-17 is promising for research of cancers.