GENERAL CATALOGUE
EGFR-IN-1 hydrochloride
HY-19617A · 5 mg
MedChemExpress · Cat: HY-19617A
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Manufacturer product page
medchemexpress.com/egfr-in-1-hydrochloride.htmlCatalog No: HY-19617A
CAS No: 2227455-78-7
Category: JAK STAT Signaling
Pack Size: 5 mg
Brand: MedChemExpress
Description
EGFR-IN-1 hydrochloride is an orally active and irreversible L858R/T790M mutant selective EGFR inhibitor. EGFR-IN-1 hydrochloride potently inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. EGFR-IN-1 hydrochloride displays strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. Antitumor activity.
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