GENERAL CATALOGUE
EGFR-IN-119
HY-163880 · 50 mg
MedChemExpress · Cat: HY-163880
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Manufacturer product page
medchemexpress.com/egfr-in-119.htmlCatalog No: HY-163880
Category: GPCR G Protein
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR-IN-119 Compound 5l is an inhibitor for EGFR with an IC50 of 84.3 nM. EGFR-IN-119 inhibits the cytotoxicity in lung cancer cell A549 with an IC50 of 1.34 ?M. EGFR-IN-119 downregulates the expressions of EGFR, KRAS, and MAP2K genes, exhibits antioxidant activity through reduction of reactive oxygen species ROS , and hyperpolarizes the mitochondrial membrane potential.
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