GENERAL CATALOGUE
EGFR-IN-140
HY-170497 · 50 mg
MedChemExpress · Cat: HY-170497
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Manufacturer product page
medchemexpress.com/egfr-in-140.htmlCatalog No: HY-170497
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR-IN-140 Compound 31 is the inhibitor for EGFR, that inhibits EGFR wildtype and EGFR L858R/T790M/C797S mutant with Ki of 0.95 nM and 2.1 nM, and inhibits EGFR del19/T790M/C797S in Ba/F3 with an IC50 of 56.9 nM. EGFR-IN-140 exhibits antitumor efficacy in mouse model.
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