GENERAL CATALOGUE
EGFR-IN-48
HY-143445 · 50 mg
MedChemExpress · Cat: HY-143445
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Manufacturer product page
medchemexpress.com/egfr-in-48.htmlCatalog No: HY-143445
CAS No: 2882851-77-4
Category: JAK STAT Signaling
Pack Size: 50 mg
Brand: MedChemExpress
Description
EGFR-IN-48 is a potent and orally active EGFR inhibitor with IC50s of 0.193 nM, 0.251 nM, 10.4 nM for EGFRd19/TM/CS, EGFRLR/TM/CS, EGFRWT, respectively. EGFR-IN-48 inhibits the proliferation of BaF3EGFR del19/T790M/C797S and PC-9EGFR del19/T790M/C797S cells with IC50s of 1.526, 66.7 nM, respectively.
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