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EGFR mutant-IN-2
GENERAL CATALOGUE

EGFR mutant-IN-2

HY-155005 · 5 mg

MedChemExpress · Cat: HY-155005

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Catalog No: HY-155005
CAS No: 2770009-06-6
Category: JAK STAT Signaling
Pack Size: 5 mg
Brand: MedChemExpress

Description

EGFR mutant-IN-2 Compound D51 is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFRL858R/T790M/C797S mutant with an IC50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFRdel19/T790M/C797S mutant with an IC50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity.

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