EGFR mutant Mouse Monoclonal Antibody

Description

EnkiLife offers the EGFR mutant Mouse Monoclonal Antibody. This antibody reacts with Human species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: ERBB; HER1; mENA; ERBB1; PIG61. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. Research Area: TGF-beta signaling pathway,PI3K-Akt signaling pathway,MAPK signaling pathway,Jak-STAT signaling pathway,Hippo signaling pathway