GENERAL CATALOGUE
Eggmanone
HY-121037 · 1 mg
MedChemExpress · Cat: HY-121037
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Catalog No: HY-121037
CAS No: 505068-32-6
Category: Metabolic Enzyme Protease
Pack Size: 1 mg
Brand: MedChemExpress
Description
Eggmanone EGM1 is a potent and selective phosphodiesterase 4 PDE4 antagonist with an IC50 of 72 nM for PDE4D3. Eggmanone shows approximately 40- to 50-fold selective for PDE4D3 over other PDEs. Eggmanone exerts its Hh-inhibitory effects through selective antagonism of PDE4, leading to protein kinase A activation and subsequent Hh blockade.
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