Eicosapentaenoic acid (metformin)

Description

Eicosapentaenoic Acid EPA metformin is an orally active Omega-3 long-chain polyunsaturated fatty acid ?-3 LC-PUFA . Eicosapentaenoic acid metformin exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein ? C/EBP? . EEicosapentaenoic acid metformin activates RAS/ERK/C/EBP? pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic acid metformin can promote relaxation of vascular smooth muscle cells and vasodilation.