EIF2AK2 Mouse Monoclonal Antibody

Description

EnkiLife offers the EIF2AK2 Mouse Monoclonal Antibody. This antibody reacts with Human,Mouse,Rat,Rabbit species and is suitable for WB,IHC,ELISA,FC application. Alternative Names of Immunogen: PKR; PRKR; EIF2AK1. The product boasts remarkable high specificity, outstanding reproducibility, and exceptional affinity, making it a reliable and superior choice for your needs. Dilution Ratio: WB 1:500-1:2000,IHC 1:100-1:500,ELISA 1:5000-1:20000,FC 1:200-1:400 Background: The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.