GENERAL CATALOGUE
eIF4E/eIF4G PPI-IN-1
HY-176288 · 50 mg
MedChemExpress · Cat: HY-176288
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medchemexpress.com/eif4e-eif4g-ppi-in-1.html
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Catalog No: HY-176288
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
eIF4E/eIF4G PPI-IN-1 is an eIF4E/eIF4G interaction inhibitor with a KD of 20.2 ?M for eIF4E protein. eIF4E/eIF4G PPI-IN-1 plays an antitumor role in multiple modes of action including regulating the activity of eIF4E by inhibiting the Ras/MAPK/eIF4E signaling pathway, apoptosis and cell migration. eIF4E/eIF4G PPI-IN-1 suppresses the growth of HepG2 xenografts in nude mice and was relatively nontoxic to mice.
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