GENERAL CATALOGUE
Elebsiran
HY-147266A · 50 mg
MedChemExpress · Cat: HY-147266A
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Catalog No: HY-147266A
CAS No: 2648009-64-5
Category: Anti-infection
Pack Size: 50 mg
Brand: MedChemExpress
Description
Elebsiran VIR-2218 is a siRNA that targets and degrades hepatitis B virus HBV and hepatitis D virus HDV RNA transcripts. Elebsiran leads to a significant decrease in HBV surface antigen HBsAg and a reduction in viral load. Elebsiran binds to the sialic acid-depleted glycoprotein receptor ASGPR on the surface of liver cells through the GalNAc ligand, achieving liver-targeted delivery and demonstrating improved liver safety. Elebsiran can be used for the study of chronic HBV/HDV infections.
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