

HY-101999 · 50 mg
MedChemExpress · Cat: HY-101999
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medchemexpress.com/em20-25.htmlDescription
EM20-25 is an inhibitor for Bcl-2, which interferes with the interaction between BCL-2 and BAX, activates caspase-9 and thus induces the apoptosis. EM20-25 affects the mitochondrial function, causes the open of permeability transition pore PTP . EM20-25 enhances the sensitivity of cells to Staurosporine HY-15141 , and enhances the killing effect of BCL-2-expressing leukemia cells to Chlorambucil HY-13593 and Fludarabine HY-B0069 .







