

HY-135317 · Free Sample (0.1 - 0.2 mg)
MedChemExpress · Cat: HY-135317
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Manufacturer product page
medchemexpress.com/emavusertib.html
Description
Emavusertib is an orally active inhibitor for IRAK4 IC50=57 nM and FLT3. Emavusertib inhibits NF-?B and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib exhibits antitumor activity in mouse model







