GENERAL CATALOGUE
Emavusertib hydrochloride
HY-135317B · 50 mg
MedChemExpress · Cat: HY-135317B
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Manufacturer product page
medchemexpress.com/emavusertib-hydrochloride.htmlCatalog No: HY-135317B
CAS No: 2376399-42-5
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Emavusertib hydrochloride CA-4948 tosylate is the hydrochloride salt form of Emavusertib HY-135317 . Emavusertib hydrochloride is an orally active inhibitor for IRAK4 IC50=57 nM and FLT3. Emavusertib hydrochloride inhibits NF-?B and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib hydrochloride exhibits antitumor activity in mouse model.
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