GENERAL CATALOGUE
Emavusertib maleate
HY-135317E · 50 mg
MedChemExpress · Cat: HY-135317E
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medchemexpress.com/emavusertib-maleate.htmlCatalog No: HY-135317E
CAS No: 2376399-39-0
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Emavusertib maleate CA-4948 maleate is the maleate salt form of Emavusertib HY-135317 . Emavusertib maleate is an orally active inhibitor for IRAK4 IC50=57 nM and FLT3. Emavusertib maleate inhibits NF-?B and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib maleate exhibits antitumor activity in mouse model.
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