GENERAL CATALOGUE
Emavusertib tosylate
HY-135317C · 50 mg
MedChemExpress · Cat: HY-135317C
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Catalog No: HY-135317C
CAS No: 2376399-41-4
Category: Apoptosis
Pack Size: 50 mg
Brand: MedChemExpress
Description
Emavusertib tosylate CA-4948 tosylate is the tosylate salt form of Emavusertib HY-135317 . Emavusertib tosylate is an orally active inhibitor for IRAK4 IC50=57 nM and FLT3. Emavusertib tosylate inhibits NF-?B and MyD88 signaling pathways, reduces the generation of pro-inflammatory cytokines like IL-6 and IL-10, thereby exhibiting anti-inflammatory and anti-proliferative activities against cancer cells, leading to cell apoptosis. Emavusertib tosylate exhibits antitumor activity in mouse model.
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