Embelin (Standard)

Description

Embelin Standard is the analytical standard of Embelin. This product is intended for research and analytical applications. Embelin Embelic acid , a potent, nonpeptidic XIAP inhibitor IC50=4.1 ?M , inhibits cell growth, induces apoptosis, and activates caspase-9 in prostate cancer cells with high levels of XIAP. Embelin blocks NF-kappaB signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Embelin also induces autophagic and apoptotic cell death in human oral squamous cell carcinoma cells.