Enoxacin-d8 hydrate

Description

Enoxacin-d8 hydrate is deuterium labeled Enoxacin. Enoxacin AT 2266 , a fluoroquinolone, interferes with DNA replication and inhibits bacterial DNA gyrase IC50=126 ?g/ml and topoisomerase IV IC50=26.5 ?g/ml . Enoxacin is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs. Enoxacin has potent activities against gram-positive and -negative bacteria. Enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 TRBP -mediated microRNA processing.